Last update 20 Mar 2025

Trop2/CD3 bispecific antibody(Arbele)

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
TROP-2/CD3 bispecific antibodies (Arbele)
Target
CD3 x Trop-2
Action
modulators, stimulants, inhibitors
Mechanism
CD3 modulators(T cell surface glycoprotein CD3 modulators), CD3 stimulants(T cell surface glycoprotein CD3 stimulants), Trop-2 inhibitors(Tumor-associated calcium signal transducer 2 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Gastrointestinal NeoplasmsColorectal CancerPancreatic Cancer+ [1]
Inactive Indication-
Originator Organization
Arbele Corp.Arbele Corp.Startup
Active Organization
Arbele Corp.Arbele Corp.Startup
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Trop2/CD3 bispecific antibody(Arbele)
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100 Translational Medicine associated with Trop2/CD3 bispecific antibody(Arbele)
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100 Patents (Medical) associated with Trop2/CD3 bispecific antibody(Arbele)
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100 Deals associated with Trop2/CD3 bispecific antibody(Arbele)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Gastrointestinal NeoplasmsPreclinical
Hong Kong
Arbele Corp.Arbele Corp.Startup
22 Mar 2024
Colorectal CancerPreclinical
China
Arbele Corp.Arbele Corp.Startup
-
Pancreatic CancerPreclinical
China
Arbele Corp.Arbele Corp.Startup
-
Stomach CancerPreclinical
China
Arbele Corp.Arbele Corp.Startup
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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