Last update 21 Nov 2024
Cenicriviroc mesylate/Tropifexor
Last update 21 Nov 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms Cenicriviroc/tropifexor, Tropifexor/Cenicriviroc + [1] |
Target |
Mechanism CCR2 antagonists(C-C chemokine receptor type 2 antagonists), CCR5 antagonists(C-C chemokine receptor type 5 antagonists), FXR agonists(Bile acid receptor FXR agonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
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Structure
Molecular FormulaC29H25F4N3O5S |
InChIKeyVYLOOGHLKSNNEK-PIIMJCKOSA-N |
CAS Registry1383816-29-2 |
View All Structures (2)
Related
2
Clinical Trials associated with Cenicriviroc mesylate/TropifexorA randomized, double-blind, placebo controlled, 3- part,adaptive design, multicenter study to assesssafety, tolerability and efficacy of tropifexor (LJN452) in patients withnon-alcoholic steatohepatitis (NASH) - NASH
A Randomized, Double-blind, Placebo Controlled, 3- Part, Adaptive Design, Multicenter Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in Patients With Non-alcoholic Steatohepatitis (NASH): FLIGHT-FXR
100 Clinical Results associated with Cenicriviroc mesylate/Tropifexor
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100 Translational Medicine associated with Cenicriviroc mesylate/Tropifexor
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100 Patents (Medical) associated with Cenicriviroc mesylate/Tropifexor
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100 Deals associated with Cenicriviroc mesylate/Tropifexor
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Nonalcoholic Steatohepatitis | Phase 2 | SG | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | IT | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | IT | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | ES | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | NL | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | NL | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | SG | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | DE | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | ES | 01 Aug 2016 | |
| Nonalcoholic Steatohepatitis | Phase 2 | DE | 01 Aug 2016 |
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