Last update 08 Feb 2025

Evogliptin Tartrate/Metformin Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Evogliptin/metformin, Sugamet, DA-1229_01
+ [1]
Target
DPP-4 x PRKAB1
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors), PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication
Diabetes Mellitus, Type 2
Inactive Indication-
Originator Organization
Dong-A Pharmaceutical Co., Ltd.Dong-A Pharmaceutical Co., Ltd.
Active Organization
Dong-A Pharmaceutical Co., Ltd.Dong-A Pharmaceutical Co., Ltd.Dong-A ST Co., Ltd.Dong-A ST Co., Ltd.
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
KR (31 Dec 2015),
Diabetes Mellitus, Type 2
Regulation-
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Structure/Sequence

Molecular FormulaC4H12ClN5
InChIKeyOETHQSJEHLVLGH-UHFFFAOYSA-N
CAS Registry1115-70-4
View All Structures (2)

Related

9
Clinical Trials associated with Evogliptin Tartrate/Metformin Hydrochloride
NCT05739916
/ Not yet recruitingPhase 1
An Open Label, Randomized, Single Dose, Cross-over ,Two-group Study to Evaluate the Pharmacokinetics and Safety of DA-1229_01 5/1000mg in Healthy Subjects at Fed State
NCT05739903
/ Not yet recruitingPhase 1
An Open Label, Randomized, Single Dose, Cross-over ,Two-group Study to Evaluate the Pharmacokinetics and Safety of DA-1229_01 5/1000mg in Healthy Subjects at Fasting State
NCT05739851
/ Not yet recruitingPhase 1
An Open Label, Randomized, Single Dose, Cross-over ,Two-group Study to Evaluate the Pharmacokinetics and Safety of DA-1229_01 2.5/500mg in Healthy Subjects at Fasting State
100 Clinical Results associated with Evogliptin Tartrate/Metformin Hydrochloride
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100 Translational Medicine associated with Evogliptin Tartrate/Metformin Hydrochloride
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100 Patents (Medical) associated with Evogliptin Tartrate/Metformin Hydrochloride
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100 Deals associated with Evogliptin Tartrate/Metformin Hydrochloride
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External Link

KEGGWikiATCDrug Bank
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A10BD22
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
KR
Dong-A Pharmaceutical Co., Ltd.Dong-A Pharmaceutical Co., Ltd.
31 Dec 2015
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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