Last update 31 Jan 2026

Anti-CD2/CD3/ULBP2 trispecific T cell engager(EvolveImmune Therapeutics)

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms-
Target
CD2 x CD3 x ULBP2
Action
agonists, stimulants, inhibitors
Mechanism
CD2 agonists(T-cell surface antigen CD2 agonists), CD3 stimulants(T cell surface glycoprotein CD3 stimulants), ULBP2 inhibitors(UL16 binding protein 2 inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Hematologic NeoplasmsSolid tumor
Inactive Indication-
Originator Organization
Evolveimmune Therapeutics, Inc.Evolveimmune Therapeutics, Inc.
Active Organization
Evolveimmune Therapeutics, Inc.Evolveimmune Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Anti-CD2/CD3/ULBP2 trispecific T cell engager(EvolveImmune Therapeutics)
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100 Translational Medicine associated with Anti-CD2/CD3/ULBP2 trispecific T cell engager(EvolveImmune Therapeutics)
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100 Patents (Medical) associated with Anti-CD2/CD3/ULBP2 trispecific T cell engager(EvolveImmune Therapeutics)
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100 Deals associated with Anti-CD2/CD3/ULBP2 trispecific T cell engager(EvolveImmune Therapeutics)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Hematologic NeoplasmsPreclinical
Canada
Evolveimmune Therapeutics, Inc.Evolveimmune Therapeutics, Inc.
18 Nov 2025
Solid tumorPreclinical
Canada
Evolveimmune Therapeutics, Inc.Evolveimmune Therapeutics, Inc.
18 Nov 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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