Last update 28 Jun 2025

S-44858

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
S44858
Target
AMPA receptor x GluN2B
Action
positive allosteric modulator, antagonists
Mechanism
AMPA receptor positive allosteric modulator(Glutamate receptor ionotropic AMPA positive allosteric modulator), GluN2B antagonists(Glutamate [NMDA] receptor subunit epsilon 2 antagonists)
Therapeutic Areas
Other Diseases
Active Indication
Nerve Degeneration
Inactive Indication
Alzheimer DiseaseCentral Nervous System DiseasesDepressive Disorder
Originator Organization
Les Laboratoires Servier SASLes Laboratoires Servier SAS
Active Organization
Les Laboratoires Servier SASLes Laboratoires Servier SAS
Inactive Organization
Institut de Recherches Servier SASSARL Technologie ServierHiQScreen SARLHiQScreen SARL
+ [1]
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
Login to view timeline

Related

100 Clinical Results associated with S-44858
Login to view more data
100 Translational Medicine associated with S-44858
Login to view more data
100 Patents (Medical) associated with S-44858
Login to view more data
100 Deals associated with S-44858
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Nerve DegenerationPhase 1-
Les Laboratoires Servier SASLes Laboratoires Servier SAS
-
Alzheimer DiseasePreclinical
France
Institut de Recherches Servier SAS
01 Jul 2015
Central Nervous System DiseasesPreclinical
France
SARL Technologie Servier
01 Jul 2015
Central Nervous System DiseasesPreclinical
France
Neurofit VR, Inc.Neurofit VR, Inc.
01 Jul 2015
Central Nervous System DiseasesPreclinical
Switzerland
HiQScreen SARLHiQScreen SARL
01 Jul 2015
Depressive DisorderPreclinical
France
SARL Technologie Servier
01 Jul 2015
Depressive DisorderPreclinical
France
Institut de Recherches Servier SAS
01 Jul 2015
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free