Last update 25 Nov 2024
GB-251
Last update 25 Nov 2024
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms GB 251, NBT 828, NBT-828 + [1] |
Target |
Mechanism HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), Tubulin inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 1 |
First Approval Date- |
RegulationSpecial Review Project (CN) |
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Structure
Molecular FormulaC11H22N4O4 |
InChIKeyAGGWFDNPHKLBBV-YUMQZZPRSA-N |
CAS Registry159858-33-0 |
View All Structures (2)
Related
1
Clinical Trials associated with GB-251注射用GB251在HER-2阳性转移性乳腺癌患者中开放、剂量递增、单次给药的耐受性，安全性，药代动力学及免疫原性特征的Ia期临床研究
[Translation] Phase Ia clinical study of the tolerability, safety, pharmacokinetics and immunogenicity of GB251 for injection in patients with HER-2 positive metastatic breast cancer with open-label, dose-escalation and single-dose administration
100 Clinical Results associated with GB-251
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100 Translational Medicine associated with GB-251
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100 Patents (Medical) associated with GB-251
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100 Deals associated with GB-251
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| HER2 Positive Breast Cancer | Phase 1 | CN | 13 Apr 2021 | |
| Breast Cancer | Phase 1 | CN | - | |
| Stomach Cancer | Phase 1 | CN | - |
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Clinical Result
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