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Last update 22 Mar 2025
CLBR-001
Last update 22 Mar 2025
Overview
Basic Info
Drug Type Autologous CAR-T |
Synonyms- |
Target |
Action inhibitors |
Mechanism CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
2
Clinical Trials associated with CLBR-001NCT06878248
A Phase 1, Open-Label, Dose-Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Combination of CLBR001, an Engineered Autologous T Cell Product, and ABBV-461, an Antibody-Based Biologic, in Subjects With Locally Advanced or Metastatic Breast Cancer
NCT04488354
A Study to Evaluate the Long-Term Safety of CLBR001, A Lentiviral Based Chimeric Antigen Receptor, In Patients With B-Cell Malignancies Previously Administered CLBR001
100 Clinical Results associated with CLBR-001
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100 Translational Medicine associated with CLBR-001
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100 Patents (Medical) associated with CLBR-001
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100 Deals associated with CLBR-001
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| HER2 Positive Breast Cancer | Phase 1 | - | 01 Apr 2025 | |
| Hormone receptor positive breast cancer | Phase 1 | - | 01 Apr 2025 | |
| Locally advanced breast cancer | Phase 1 | - | 01 Apr 2025 | |
| Metastatic breast cancer | Phase 1 | - | 01 Apr 2025 | |
| Triple Negative Breast Cancer | Phase 1 | - | 01 Apr 2025 | |
| Burkitt Lymphoma | Phase 1 | United States | 21 Jan 2021 | |
| Chronic Lymphocytic Leukemia | Phase 1 | United States | 21 Jan 2021 | |
| Follicular Lymphoma | Phase 1 | United States | 21 Jan 2021 | |
| Lymphoplasmacytic Lymphoma | Phase 1 | United States | 21 Jan 2021 | |
| Mantle-Cell Lymphoma | Phase 1 | United States | 21 Jan 2021 |
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