Last update 22 Mar 2025

C402-CD19-CAR

Overview

Basic Info

Drug Type
CAR-T
Synonyms
C402 CD19 CAR, C402-CD19 CAR
Target
CD19
Action
inhibitors
Mechanism
CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication
CD19 positive B-Cell LymphomaFollicular LymphomaHigh grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements+ [3]
Inactive Indication-
Originator Organization
EXUMA Biotech Corp.
Active Organization
Shanghai Exuma Biotechnology Ltd.StartupEXUMA Biotech Corp.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with C402-CD19-CAR
NCT06830031
/ Not yet recruitingPhase 1
A Phase 1 Study of C402-CD19-CAR, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Targeting CD19 in Subjects With Relapsed or Refractory Large B-cell Lymphoma
100 Clinical Results associated with C402-CD19-CAR
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100 Translational Medicine associated with C402-CD19-CAR
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100 Patents (Medical) associated with C402-CD19-CAR
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100 Deals associated with C402-CD19-CAR
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CD19 positive B-Cell LymphomaPhase 1
China
Shanghai Exuma Biotechnology Ltd.Startup
24 Feb 2025
Follicular LymphomaPhase 1
China
Shanghai Exuma Biotechnology Ltd.Startup
24 Feb 2025
High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangementsPhase 1
China
Shanghai Exuma Biotechnology Ltd.Startup
24 Feb 2025
Mediastinal large B-cell lymphomaPhase 1
China
Shanghai Exuma Biotechnology Ltd.Startup
24 Feb 2025
Autoimmune DiseasesPreclinical
United States
EXUMA Biotech Corp.
01 Dec 2024
Large B-cell lymphomaPreclinical
United States
EXUMA Biotech Corp.
01 Dec 2024
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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