Last update 21 Nov 2024

Lu-AG22515

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
Target
CD40L x albumin
Mechanism
CD40L modulators(CD40 ligand modulators), albumin antagonists(Serum albumin antagonists)
Therapeutic Areas
Immune System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
Graves OphthalmopathyAutoimmune Diseases
Inactive Indication-
Originator Organization
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
Active Organization
H. Lundbeck A/SH. Lundbeck A/SAprilbio Co. Ltd.Aprilbio Co. Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with Lu-AG22515
NCT06557850 / RecruitingPhase 1
Interventional, Open-label, Single-group, Long-term Follow-up Trial of Lu AG22515 in Patients With Moderate-to-severe Thyroid Eye Disease
NCT05136053 / CompletedPhase 1
A Phase 1, 3-Part, Single Ascending Dose, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Lu AG22515 (APB-A1) in Healthy Adult Subjects
100 Clinical Results associated with Lu-AG22515
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100 Translational Medicine associated with Lu-AG22515
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100 Patents (Medical) associated with Lu-AG22515
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100 Deals associated with Lu-AG22515
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Graves OphthalmopathyPhase 1
BG
H. Lundbeck A/SH. Lundbeck A/S
19 Sep 2024
Autoimmune DiseasesPhase 1
US
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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