Last update 25 Jan 2025

GATE-101

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
mGluR2 x mGluR3
Mechanism
mGluR2 antagonists(Metabotropic glutamate receptor 2 antagonists), mGluR3 antagonists(Metabotropic glutamate receptor 3 antagonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Depressive Disorder, MajorIdiopathic Hypersomnia
Originator Organization-
Active Organization-
Inactive Organization
Gate Neurosciences, Inc.Gate Neurosciences, Inc.Startup
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with GATE-101
NCT04618263
/ TerminatedPhase 1
A Randomized Double-blind, Placebo-controlled Single and Multiple Intravenous Ascending Dose Study of the Safety, Tolerability and Pharmacokinetics of GATE-101 in Normal Healthy Volunteers
100 Clinical Results associated with GATE-101
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100 Translational Medicine associated with GATE-101
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100 Patents (Medical) associated with GATE-101
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100 Deals associated with GATE-101
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Depressive Disorder, MajorPhase 1
US
Gate Neurosciences, Inc.Gate Neurosciences, Inc.Startup
26 Oct 2020
Idiopathic HypersomniaPhase 1
US
Gate Neurosciences, Inc.Gate Neurosciences, Inc.Startup
26 Oct 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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