Last update 15 Jun 2026

Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product(Direct Biologics)

Overview

Basic Info

Drug Type
Exosomes, Mesenchymal stem cell therapy
Synonyms
DB-3Q
Target-
Action-
Mechanism-
Therapeutic Areas
Immune System DiseasesDigestive System DisordersOther Diseases
Active Indication
Crohn DiseasePerianal fistula due to Crohn's disease
Inactive Indication-
Originator Organization
Direct Biologics LLCDirect Biologics LLC
Active Organization
Direct Biologics LLCDirect Biologics LLC
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product(Direct Biologics)
NCT07625293
/ Not yet recruitingPhase 2
A Phase 2a Study of DB-3Q for the Treatment of Medically Refractory Crohn's Disease
NCT06918808
/ RecruitingPhase 2
A Phase 2a Study of Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product (DB-3Q) in Patients With Perianal Fistulizing Crohn's Disease
100 Clinical Results associated with Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product(Direct Biologics)
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100 Translational Medicine associated with Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product(Direct Biologics)
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100 Patents (Medical) associated with Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product(Direct Biologics)
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100 Deals associated with Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product(Direct Biologics)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Crohn DiseasePhase 2
United States
Direct Biologics LLCDirect Biologics LLC
01 Jun 2026
Perianal fistula due to Crohn's diseasePhase 2
United States
Direct Biologics LLCDirect Biologics LLC
19 May 2025
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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