Last update 29 Nov 2024

CDK2 (Plexium)

Overview

Basic Info

Drug Type
Molecular glue
Synonyms
CDK2 bivalent degrader(Plexium)
Target
CDK2 x CRBN
Mechanism
CDK2 modulators(Cyclin-dependent kinase 2 modulators), CRBN inhibitors(Cereblon inhibitors)
Therapeutic Areas
NeoplasmsEndocrinology and Metabolic DiseaseSkin and Musculoskeletal Diseases+ [1]
Active Indication
Breast CancerEndometrial CarcinomaOvarian Cancer+ [1]
Inactive Indication-
Originator Organization
Plexium, Inc.Plexium, Inc.Startup
Active Organization
Plexium, Inc.Plexium, Inc.Startup
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CDK2 (Plexium)
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100 Translational Medicine associated with CDK2 (Plexium)
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100 Patents (Medical) associated with CDK2 (Plexium)
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100 Deals associated with CDK2 (Plexium)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPreclinical
US
Plexium, Inc.Plexium, Inc.Startup
08 Jun 2024
Endometrial CarcinomaPreclinical
US
Plexium, Inc.Plexium, Inc.Startup
08 Jun 2024
Ovarian CancerPreclinical
US
Plexium, Inc.Plexium, Inc.Startup
08 Jun 2024
ER-positive/HER2-negative Breast CancerDiscovery
US
Plexium, Inc.Plexium, Inc.Startup
05 Jan 2024
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Clinical Result

Indication
Phase
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Approval

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Regulation

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