Last update 29 Dec 2025

Coptisine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
NLRP3 x ROS1 x SIRT1 x TXNIP
Action
inhibitors, stimulants
Mechanism
NLRP3 inhibitors(NACHT, LRR and PYD domains-containing protein 3 inhibitors), ROS1 inhibitors(Proto-oncogene tyrosine-protein kinase ROS inhibitors), SIRT1 stimulants(NAD-dependent deacetylase sirtuin 1 stimulants)
Therapeutic Areas
Immune System DiseasesDigestive System DisordersRespiratory Diseases+ [1]
Active Indication
Inflammatory Bowel DiseasesLung Injury
Inactive Indication-
Originator Organization
Zunyi Medical UniversityZunyi Medical UniversityChengdu DeSiTe Biological Technology Co., Ltd.Chengdu DeSiTe Biological Technology Co., Ltd.
Active Organization
Zunyi Medical UniversityZunyi Medical UniversityChengdu DeSiTe Biological Technology Co., Ltd.Chengdu DeSiTe Biological Technology Co., Ltd.Chengdu University of Traditional Chinese MedicineChengdu University of Traditional Chinese Medicine
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Coptisine
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100 Translational Medicine associated with Coptisine
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100 Patents (Medical) associated with Coptisine
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100 Deals associated with Coptisine
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Inflammatory Bowel DiseasesPreclinical
China
Zunyi Medical UniversityZunyi Medical University
01 Dec 2025
Inflammatory Bowel DiseasesPreclinical
China
Chengdu DeSiTe Biological Technology Co., Ltd.Chengdu DeSiTe Biological Technology Co., Ltd.
01 Dec 2025
Lung InjuryPreclinical
China
Chengdu University of Traditional Chinese MedicineChengdu University of Traditional Chinese Medicine
01 Aug 2025
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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