Last update 08 Nov 2025

CYRS-1542

Overview

Basic Info

Drug Type
Degradable Molecular Glue
Synonyms
CYRS 1542, CYRS1542
Target
GSPT1
Action
degraders
Mechanism
GSPT1 degraders(G1 to S phase transition 1 degraders)
Therapeutic Areas
NeoplasmsHemic and Lymphatic DiseasesRespiratory Diseases+ [1]
Active Indication
Neuroendocrine TumorsProstate Neuroendocrine CarcinomaSmall Cell Lung Cancer+ [2]
Inactive Indication-
Originator Organization
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.
Active Organization
Seoul National UniversitySeoul National UniversityCyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.
St. Jude Children's Research Hospital, Inc.St. Jude Children's Research Hospital, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CYRS-1542
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100 Translational Medicine associated with CYRS-1542
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100 Patents (Medical) associated with CYRS-1542
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100 Deals associated with CYRS-1542
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neuroendocrine TumorsPreclinical
South Korea
Seoul National UniversitySeoul National University
27 Apr 2025
Neuroendocrine TumorsPreclinical
South Korea
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.
27 Apr 2025
Prostate Neuroendocrine CarcinomaPreclinical
South Korea
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.
22 Mar 2024
Small Cell Lung CancerPreclinical
South Korea
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.
22 Mar 2024
Hematologic NeoplasmsPreclinical
South Korea
St. Jude Children's Research Hospital, Inc.St. Jude Children's Research Hospital, Inc.
04 Jan 2024
Hematologic NeoplasmsPreclinical
South Korea
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.
04 Jan 2024
Solid tumorPreclinical
South Korea
St. Jude Children's Research Hospital, Inc.St. Jude Children's Research Hospital, Inc.
04 Jan 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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