Pefloxacin Mesilate

Defect engineering is a promising approach for constructing highly efficient catalytic activity based on metal-organic frameworks (MOFs).In this study, a defective MOFs, referred to as quasi-MIL-100(Fe), was synthesized by moderate synthesis method and then careful thermal treatment at an atm. ranging from 150 to 450°C, linking crystalline materials and the associated metal oxides.MIL-100(Fe) heat-treated at 250°C (referred to as M-250) partially breaks coordination bonds, resulting in a crystalline-to-amorphous transformation, increased porosity, and elimination of ligands.Compared to pristine MIL-100(Fe), M-250 possessed more reactive sites and exhibited the highest photo-Fenton degradation of ciprofloxacin with 95.6% removal efficiency in 90 min, despite the unfavorable photo properties for photo-Fenton performance due to the destruction of the crystal structure.Addnl., d. functional theory (DFT) calculations, combined with free radical quenching and mass spectrometry anal., elucidated the catalytic mechanism.These findings highlight the significant potential of quasi-MOFs for applications in the photo-Fenton reaction.

In this study, core-shell magnetic molecularly imprinted polymers (MMIPs) were rationally designed using Fe₃O₄@SiO₂ nanoparticles as carriers for selective recognition and extraction of ciprofloxacin (CIP) in milk matrixes.Compared with the reported molecularly imprinted polymers, The synthesized MMIPs demonstrated exceptional magnetic responsiveness enabling rapid solid-liquid separationStatic and dynamic adsorption studies revealed a maximum CIP adsorption capacity of 11.64 mg/g, Scatchard model anal. identified two distinct binding sites: high-affinity and low-affinity sites.Pseudo-second-order kinetics indicating chemisorption-dominated binding.Moreover, selective adsorption experiments confirmed high specificity toward CIP adsorption, with no significant interference from structural analogs.Coupled with HPLC-DAD, the method achieved sensitive detection of CIP with limits of detection (LOD) and limits of quantification (LOQ) values of 0.86 g/L and 2.6 g/L, resp.In the practical application of com. samples, the recovery rate was 84.11-99.11%, and the precision (RSD)was 0.5-1.21%, demonstrating robustness for CIP enrichment in complex milk products.