Last update 14 Apr 2025

LCI133

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LCI-133
Target
AURK x CDK4 x CDK6 x CDK9 x PI3Ks
Action
inhibitors
Mechanism
AURK inhibitors(Serine/threonine-protein kinase Aurora inhibitors), CDK4 inhibitors(Cyclin-dependent kinase 4 inhibitors), CDK6 inhibitors(Cyclin-dependent kinase 6 inhibitors)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal DiseasesUrogenital Diseases+ [1]
Active Indication
Ewing SarcomaEndometrial Carcinoma
Inactive Indication-
Originator Organization
Atrium Health, Inc.Atrium Health, Inc.
Active Organization
Atrium Health, Inc.Atrium Health, Inc.
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with LCI133
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100 Translational Medicine associated with LCI133
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100 Patents (Medical) associated with LCI133
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100 Deals associated with LCI133
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ewing SarcomaPreclinical
United States
Atrium Health, Inc.Atrium Health, Inc.
28 Apr 2025
Endometrial CarcinomaPreclinical
United States
Atrium Health, Inc.Atrium Health, Inc.
31 May 2023
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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