Last update 23 Jan 2025

MZ4

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
VHL-targeting PROTAC compound 5
Target
BRD2 x BRD3 x BRD4
Mechanism
BRD2 inhibitors(Bromodomain-containing protein 2 inhibitors), BRD3 inhibitors(Bromodomain-containing protein 3 inhibitors), BRD4 degraders(Bromodomain-containing protein 4 degraders)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Hematologic NeoplasmsSolid tumor
Inactive Indication-
Originator Organization-
Active Organization
University Of DundeeUniversity Of DundeeMedchemexpress LLCMedchemexpress LLC
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC47H56ClN9O7S2
InChIKeyUAQDCZFGBBSHLT-PBSGCNNPSA-N
CAS Registry2010159-46-1

Related

100 Clinical Results associated with MZ4
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100 Translational Medicine associated with MZ4
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100 Patents (Medical) associated with MZ4
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100 Deals associated with MZ4
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hematologic NeoplasmsPreclinical
GB
University Of DundeeUniversity Of Dundee
08 Jun 2017
Hematologic NeoplasmsPreclinical
US
Medchemexpress LLCMedchemexpress LLC
08 Jun 2017
Solid tumorPreclinical
GB
University Of DundeeUniversity Of Dundee
08 Jun 2017
Solid tumorPreclinical
US
Medchemexpress LLCMedchemexpress LLC
08 Jun 2017
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Clinical Result

Indication
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Approval

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Regulation

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