Drug Type Small molecule drug |
Synonyms Bindarit (USAN/INN), AF-2838 |
Target |
Action inhibitors |
Mechanism CCL2 inhibitors(C-C motif chemokine 2 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
RegulationOrphan Drug (United States) |
Molecular FormulaC19H20N2O3 |
InChIKeyMTHORRSSURHQPZ-UHFFFAOYSA-N |
CAS Registry130641-38-2 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Coronary Restenosis | Phase 2 | Italy | 01 Jan 2009 | |
Albuminuria | Phase 2 | Italy | 01 Mar 2007 | |
Albuminuria | Phase 2 | Slovenia | 01 Mar 2007 | |
Diabetic Nephropathies | Phase 2 | Italy | 01 Mar 2007 | |
Diabetic Nephropathies | Phase 2 | Slovenia | 01 Mar 2007 | |
Lupus Nephritis | Phase 2 | Italy | - | |
Rheumatoid Arthritis | Phase 2 | United States | - | |
Rheumatoid Arthritis | Phase 2 | Italy | - | |
Rheumatoid Arthritis | Phase 2 | United Kingdom | - | |
Pancreatitis | Preclinical | Italy | - |
Not Applicable | - | Bindarit 600 mg twice daily | yalgunxyin(fumqocdvtb) = ddjzowqkuf bjdtetoaps (rdsbzvpteb ) | Positive | 16 Nov 2010 | ||
Placebo | yalgunxyin(fumqocdvtb) = faykdmjjsz bjdtetoaps (rdsbzvpteb ) |