Last update 03 Aug 2026

VBC106

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
VBC-106
Target
FOLR1 x MSLN x Top I
Action
antagonists, inhibitors
Mechanism
FOLR1 antagonists(Folate receptor alpha antagonists), MSLN inhibitors(Mesothelin inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid NeoplasmSolid tumor
Inactive Indication-
Originator Organization
Velavigo Shanghai Pharmaceutical Co.,LtdVelavigo Shanghai Pharmaceutical Co.,Ltd
Active Organization
Velavigo Shanghai Pharmaceutical Co.,LtdVelavigo Shanghai Pharmaceutical Co.,LtdVelaVigo Bio Inc
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with VBC106
NCT07686068
/ Not yet recruitingPhase 1/2
Phase 1/2a Open-Label Clinical Trial Evaluating VBC106, an FRα- and MSLN-Directed Bispecific Antibody Drug Conjugate, in Participants With Advanced Malignant Solid Tumors
100 Clinical Results associated with VBC106
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100 Translational Medicine associated with VBC106
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100 Patents (Medical) associated with VBC106
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100 Deals associated with VBC106
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
United States
VelaVigo Bio Inc
18 Aug 2026
Advanced Malignant Solid NeoplasmPhase 2
Australia
VelaVigo Bio Inc
18 Aug 2026
Solid tumorDiscovery
China
Velavigo Shanghai Pharmaceutical Co.,LtdVelavigo Shanghai Pharmaceutical Co.,Ltd
15 Aug 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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