Last update 27 Feb 2026

Recombinant human histone H1.3(SymBio Pharmaceuticals)

Overview

Basic Info

Drug Type
Recombinant protein
Synonyms
ONCOHIST, OncoHist, Product F
+ [3]
Target
H1-3
Action
modulators, stimulants
Mechanism
H1-3 modulators(H1.3 linker histone, cluster member modulators), Apoptosis stimulants, Cell membrane modulators
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
Acute Myeloid LeukemiaNon-Hodgkin Lymphoma
Inactive Indication-
Originator Organization
SymBio Pharmaceuticals Ltd.SymBio Pharmaceuticals Ltd.
Active Organization
Xenetic Biosciences, Inc.Xenetic Biosciences, Inc.Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.SymBio Pharmaceuticals Ltd.SymBio Pharmaceuticals Ltd.
+ [1]
Inactive Organization
SymbioTec GmbH
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with Recombinant human histone H1.3(SymBio Pharmaceuticals)
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100 Translational Medicine associated with Recombinant human histone H1.3(SymBio Pharmaceuticals)
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100 Patents (Medical) associated with Recombinant human histone H1.3(SymBio Pharmaceuticals)
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100 Deals associated with Recombinant human histone H1.3(SymBio Pharmaceuticals)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 2
Germany
SymbioTec GmbH
16 Nov 2007
Non-Hodgkin LymphomaPhase 2
Russia
--
Non-Hodgkin LymphomaPhase 2-
Pharmsynthez PJSCPharmsynthez PJSC
-
Non-Hodgkin LymphomaPhase 2-
Xenetic Biosciences, Inc.Xenetic Biosciences, Inc.
-
Non-Hodgkin LymphomaPhase 2-
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
-
Non-Hodgkin LymphomaPhase 2-
SymBio Pharmaceuticals Ltd.SymBio Pharmaceuticals Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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