Last update 10 May 2025

90Y-AHN-12

Overview

Basic Info

Drug Type
Radiolabeled antibody, Diagnostic radiopharmaceuticals
Synonyms
Yttrium Y 90 anti-CD45 monoclonal antibody AHN-12(Masonic Cancer Center, University of Minnesota), 90Y AHN12, 90Y-AHN12
Target
CD45
Action
inhibitors
Mechanism
CD45 inhibitors(Leukocyte common antigen inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMyelodysplastic Syndromes+ [1]
Originator Organization
University of Minnesota Masonic Cancer Center
Active Organization-
Inactive Organization
University of Minnesota Masonic Cancer Center
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with 90Y-AHN-12
NCT01207076
/ TerminatedPhase 1IIT
Phase I Open Label, Single Arm, Dose Escalation Trial to Evaluate the Biodistribution and Safety of AHN-12 In Patients With Advanced Leukemia HM2010-05
100 Clinical Results associated with 90Y-AHN-12
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100 Translational Medicine associated with 90Y-AHN-12
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100 Patents (Medical) associated with 90Y-AHN-12
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100 Deals associated with 90Y-AHN-12
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Lymphoblastic LeukemiaPhase 1
United States
University of Minnesota Masonic Cancer Center
01 Dec 2013
Acute Myeloid LeukemiaPhase 1
United States
University of Minnesota Masonic Cancer Center
01 Dec 2013
Myelodysplastic SyndromesPhase 1
United States
University of Minnesota Masonic Cancer Center
01 Dec 2013
Philadelphia chromosome positive chronic myelogenous leukemiaPhase 1
United States
University of Minnesota Masonic Cancer Center
01 Dec 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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