Last update 20 Mar 2025

Dronedarone Hydrochloride/Ranolazine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Dronedarone/ranolazine, Ranolazine/dronedarone
Target
ADRA1 x SCNA x VDCCs x VGKCs x β1-adrenergic receptor
Action
antagonists, blockers
Mechanism
ADRA1 antagonists(Adrenergic receptor alpha-1 antagonists), SCNA blockers(Sodium channel alpha subunit blockers), VDCCs blockers(Voltage-gated calcium channel blockers)
+ [2]
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
Atrial Fibrillation
Originator Organization
Gilead Sciences, Inc.Gilead Sciences, Inc.
Active Organization-
Inactive Organization
Gilead Sciences, Inc.Gilead Sciences, Inc.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC31H45ClN2O5S
InChIKeyDWKVCQXJYURSIQ-UHFFFAOYSA-N
CAS Registry141625-93-6
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Related

100 Clinical Results associated with Dronedarone Hydrochloride/Ranolazine
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100 Translational Medicine associated with Dronedarone Hydrochloride/Ranolazine
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100 Patents (Medical) associated with Dronedarone Hydrochloride/Ranolazine
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100 Deals associated with Dronedarone Hydrochloride/Ranolazine
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Atrial FibrillationPhase 2
Germany
Gilead Sciences, Inc.Gilead Sciences, Inc.
-
Atrial FibrillationPhase 2
Italy
Gilead Sciences, Inc.Gilead Sciences, Inc.
-
Atrial FibrillationPhase 2
Israel
Gilead Sciences, Inc.Gilead Sciences, Inc.
-
Atrial FibrillationPhase 2
United States
Gilead Sciences, Inc.Gilead Sciences, Inc.
-
Atrial FibrillationPhase 2
Netherlands
Gilead Sciences, Inc.Gilead Sciences, Inc.
-
Atrial FibrillationPhase 2
United Kingdom
Gilead Sciences, Inc.Gilead Sciences, Inc.
-
Atrial FibrillationPhase 2
Poland
Gilead Sciences, Inc.Gilead Sciences, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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