Last update 28 Jan 2026

MPT-0118

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
MALT1
Action
inhibitors
Mechanism
MALT1 inhibitors(Mucosa-associated lymphoid tissue lymphoma translocation protein 1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced cancerAdvanced Malignant Solid NeoplasmNeoplasm Metastasis+ [1]
Inactive Indication
B-Cell Lymphoma
Originator Organization-
Active Organization
Monopteros Therapeutics, Inc.Monopteros Therapeutics, Inc.
Inactive Organization
Helmholtz Zentrum München Deutsches Forschungszentrum
License Organization
Monopteros Therapeutics, Inc.Monopteros Therapeutics, Inc.
Helmholtz Zentrum MünchenHelmholtz Zentrum München
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with MPT-0118
NCT04859777
/ RecruitingPhase 1
A Phase 1/1b Study of MPT-0118 as Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Refractory Solid Tumors
100 Clinical Results associated with MPT-0118
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100 Translational Medicine associated with MPT-0118
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100 Patents (Medical) associated with MPT-0118
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100 Deals associated with MPT-0118
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced cancerPhase 1
United States
Monopteros Therapeutics, Inc.Monopteros Therapeutics, Inc.
13 Apr 2021
Advanced Malignant Solid NeoplasmPhase 1
United States
Monopteros Therapeutics, Inc.Monopteros Therapeutics, Inc.
13 Apr 2021
Neoplasm MetastasisPhase 1
United States
Monopteros Therapeutics, Inc.Monopteros Therapeutics, Inc.
13 Apr 2021
Refractory CancerPhase 1
United States
Monopteros Therapeutics, Inc.Monopteros Therapeutics, Inc.
13 Apr 2021
B-Cell LymphomaPreclinical
Germany
Helmholtz Zentrum München Deutsches Forschungszentrum
05 Apr 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Clinical Trial

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Approval

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Regulation

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