Last update 21 Feb 2026

TLN-372

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TLN-372
Target
KRAS
Action
inhibitors
Mechanism
KRAS inhibitors(GTPase KRas inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
KRAS G12D mutation Solid TumorsSolid tumorKRAS mutation-related tumors
Inactive Indication-
Originator Organization
Treeline Biosciences, Inc.Treeline Biosciences, Inc.
Active Organization
Treeline Biosciences, Inc.Treeline Biosciences, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with TLN-372
NCT07204340
/ RecruitingPhase 1
An Open-Label, Multicenter, Phase 1 Trial to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of TLN-372 as a Single Agent and in Combination With Other Anti-Tumor Agents, in Patients With Advanced KRAS Mutant Solid Tumors
100 Clinical Results associated with TLN-372
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100 Translational Medicine associated with TLN-372
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100 Patents (Medical) associated with TLN-372
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100 Deals associated with TLN-372
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
KRAS G12D mutation Solid TumorsPhase 1
United States
Treeline Biosciences, Inc.Treeline Biosciences, Inc.
29 Sep 2025
KRAS G12D mutation Solid TumorsPhase 1
Australia
Treeline Biosciences, Inc.Treeline Biosciences, Inc.
29 Sep 2025
Solid tumorPhase 1
United States
Treeline Biosciences, Inc.Treeline Biosciences, Inc.
29 Sep 2025
Solid tumorPhase 1
Australia
Treeline Biosciences, Inc.Treeline Biosciences, Inc.
29 Sep 2025
KRAS mutation-related tumorsPhase 1-
Treeline Biosciences, Inc.Treeline Biosciences, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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