Last update 08 May 2025

SIR-4156

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
NAMPT activators(Sironax)
Target
NAMPT
Action
activators
Mechanism
NAMPT activators(Nicotinamide phosphoribosyltransferase activators)
Therapeutic Areas
NeoplasmsNervous System DiseasesCardiovascular Diseases+ [3]
Active Indication
Neuromuscular DiseasesCardiovascular DiseasesInflammation+ [4]
Inactive Indication-
Originator Organization
Sironax Ltd.Sironax Ltd.
Active Organization
Sironax Ltd.Sironax Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with SIR-4156
ACTRN12624001334594
/ RecruitingPhase 1
A Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SIR4156, a novel NAMPT activator, in healthy adult and elderly participants.
100 Clinical Results associated with SIR-4156
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100 Translational Medicine associated with SIR-4156
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100 Patents (Medical) associated with SIR-4156
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100 Deals associated with SIR-4156
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neuromuscular DiseasesPhase 1
Australia
Sironax Ltd.Sironax Ltd.
27 Nov 2024
Cardiovascular DiseasesPreclinical
China
Sironax Ltd.Sironax Ltd.
15 Apr 2024
InflammationPreclinical
China
Sironax Ltd.Sironax Ltd.
15 Apr 2024
Kidney DiseasesPreclinical
China
Sironax Ltd.Sironax Ltd.
15 Apr 2024
Mitochondrial DiseasesPreclinical
China
Sironax Ltd.Sironax Ltd.
15 Apr 2024
NeoplasmsPreclinical
China
Sironax Ltd.Sironax Ltd.
15 Apr 2024
Neurodegenerative DiseasesPreclinical
China
Sironax Ltd.Sironax Ltd.
15 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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