Last update 21 Nov 2024

Hydralazine Hydrochloride/Reserpine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hydropres 25, Hydropres 50, SERPASIL-APRESOLINE
+ [2]
Target
VMAT2
Mechanism
VMAT2 inhibitors(Synaptic vesicular amine transporter inhibitors)
Therapeutic Areas
Nervous System DiseasesCardiovascular DiseasesUrogenital Diseases
Active Indication
EclampsiaHypertensive Encephalopathy
Inactive Indication-
Originator Organization
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
Active Organization
Sun Pharma Japan Ltd.
Inactive Organization
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
Drug Highest PhaseApproved
First Approval Date
US (01 Apr 1954)
Regulation-
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Structure

Molecular FormulaC33H40N2O9
InChIKeyQEVHRUUCFGRFIF-MDEJGZGSSA-N
CAS Registry50-55-5
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Related

100 Clinical Results associated with Hydralazine Hydrochloride/Reserpine
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100 Translational Medicine associated with Hydralazine Hydrochloride/Reserpine
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100 Patents (Medical) associated with Hydralazine Hydrochloride/Reserpine
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2
Literatures (Medical) associated with Hydralazine Hydrochloride/Reserpine
01 Feb 1970Current therapeutic research, clinical and experimental
A double-blind evaluation of the therapeutic efficacy of salutensin versus hydropres-50 in essential hypertension.
20 Aug 1955Schweizerische medizinische Wochenschrift
[Chemotherapy in hypertension; clinical experience with serpasil, serpasil-retalin and serpasilnepresol].
100 Deals associated with Hydralazine Hydrochloride/Reserpine
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Eclampsia
JP
Sun Pharma Japan Ltd.
21 Feb 1968
Hypertensive Encephalopathy
JP
Sun Pharma Japan Ltd.
21 Feb 1968
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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