Delving into the Latest Updates on Adenovirus-transfected DCs+ CIK(Affiliated Hospital to Academy of Military Medical Sciences) with Synapse

Overview

Basic Info

Drug Type

Therapeutic vaccine, Dendritic cell vaccine

Synonyms-

Target-

Action

stimulants

Mechanism

Immunostimulants

Therapeutic Areas

NeoplasmsHemic and Lymphatic DiseasesOther Diseases

Active Indication

Acute Myeloid LeukemiaSoft Tissue Sarcoma

Inactive Indication

Renal Cell Carcinoma

Originator Organization

Affiliated Hospital to Academy of Military Medical Sciences

Active Organization

Affiliated Hospital to Academy of Military Medical Sciences

Inactive Organization-

License Organization-

Drug Highest PhasePhase 1/2

First Approval Date-

Regulation-

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The aim of this Phase I/II study is to evaluate the safety and efficacy of dendritic cells (DC) vaccine combined with cytokine-induced killer (CIK) cells in patients with renal cell carcinoma. Experimental recombinant adenovirus-transfected DC, which engineered to express MUC1 and Survivin are used for DC-based immunotherapy. Based on the results of our previously performed preclinical study with DC vaccine combined with CIK cells, the investigators plan to perform the clinical trial.

Start Date01 Jul 2013

Sponsor / Collaborator

Affiliated Hospital to Academy of Military Medical Sciences

NCT01898663

/ RecruitingPhase 1/2IIT

Safety and Therapeutic Efficacy of DCs Vaccine Combined With Cytokine-induced Killer Cells in Patients With AML: a Phase Ⅰ/Ⅱ Study

The aim of this Phase Ⅰ/Ⅱ study is to evaluate the safety and efficacy of dendritic cells (DCs) vaccine combined with cytokine-induced killer (CIK) cells in patients with AML. Experimental recombinant adenovirus-transfected DCs, which engineered to express MUC1 and Survivin are used for DCs-based immunotherapy. Based on the results of our previously performed preclinical study with DCs vaccine combined with CIK cells, the investigators plan to perform the clinical trial.

Start Date01 Jun 2013

Sponsor / Collaborator

Affiliated Hospital to Academy of Military Medical Sciences

100 Clinical Results associated with Adenovirus-transfected DCs+ CIK(Affiliated Hospital to Academy of Military Medical Sciences)

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100 Translational Medicine associated with Adenovirus-transfected DCs+ CIK(Affiliated Hospital to Academy of Military Medical Sciences)

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100 Patents (Medical) associated with Adenovirus-transfected DCs+ CIK(Affiliated Hospital to Academy of Military Medical Sciences)

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100 Deals associated with Adenovirus-transfected DCs+ CIK(Affiliated Hospital to Academy of Military Medical Sciences)

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Renal Cell Carcinoma	Phase 3	China	Affiliated Hospital to Academy of Military Medical Sciences	01 Jul 2013
Acute Myeloid Leukemia	Phase 2	China	Affiliated Hospital to Academy of Military Medical Sciences	01 Jun 2013
Soft Tissue Sarcoma	Phase 2	China	Affiliated Hospital to Academy of Military Medical Sciences	01 Jun 2013