Last update 07 Feb 2026

CSCJC3456

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CSCJC3456
Target
FGFRs x NTRK x RET x c-Kit
Action
antagonists, inhibitors
Mechanism
FGFRs antagonists(Fibroblast growth factor receptors antagonists), NTRK inhibitors(Neurotrophic tyrosine kinase receptor inhibitors), RET inhibitors(Tyrosine-protein kinase receptor RET inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced cancerAdvanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd.
Active Organization
Hebei Changshan Biochemical Pharmaceutical Co., Ltd.Hebei Changshan Biochemical Pharmaceutical Co., Ltd.Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CSCJC3456
NCT06717750
/ RecruitingPhase 1
A Single-arm, Open-label, Single/Multiple-dose Escalation, and Cohort Expansion Phase Ia/Ib Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Oral CSCJC3456 Tablets in Patients With Advanced Malignant Solid Tumors
100 Clinical Results associated with CSCJC3456
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100 Translational Medicine associated with CSCJC3456
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100 Patents (Medical) associated with CSCJC3456
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100 Deals associated with CSCJC3456
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced cancerPhase 1
China
Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd.
13 Feb 2025
Advanced Malignant Solid NeoplasmPhase 1
China
Hebei Changshan Biochemical Pharmaceutical Co., Ltd.Hebei Changshan Biochemical Pharmaceutical Co., Ltd.
06 Feb 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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