Last update 17 Apr 2025

BYON-4413

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
BYON-4413
Target
CD123 x DNA
Action
modulators, inhibitors
Mechanism
CD123 modulators(Interleukin-3 receptor subunit alpha modulators), DNA inhibitors(DNA inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Inactive Indication-
Originator Organization
Byondis BVByondis BV
Active Organization
Byondis BVByondis BV
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC11H22N4O4
InChIKeyAGGWFDNPHKLBBV-YUMQZZPRSA-N
CAS Registry159858-33-0
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Related

1
Clinical Trials associated with BYON-4413
NCT06359002
/ RecruitingPhase 1
A First-in-human Dose Escalation and Expansion Trial With the Antibody-drug Conjugate BYON4413 to Evaluate Safety, Pharmacokinetics, and Preliminary Efficacy in Patients With Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms.
100 Clinical Results associated with BYON-4413
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100 Translational Medicine associated with BYON-4413
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100 Patents (Medical) associated with BYON-4413
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100 Deals associated with BYON-4413
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 1
Belgium
Byondis BVByondis BV
25 Jun 2024
Acute Myeloid LeukemiaPhase 1
Netherlands
Byondis BVByondis BV
25 Jun 2024
Acute Myeloid LeukemiaPhase 1
Spain
Byondis BVByondis BV
25 Jun 2024
Myelodysplastic SyndromesPhase 1
Belgium
Byondis BVByondis BV
25 Jun 2024
Myelodysplastic SyndromesPhase 1
Netherlands
Byondis BVByondis BV
25 Jun 2024
Myelodysplastic SyndromesPhase 1
Spain
Byondis BVByondis BV
25 Jun 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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