Delving into the Latest Updates on Salicylic acid/Benzoic Acid with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms-

Target

COXs x DAAO

Action

inhibitors

Mechanism

COX inhibitors(Cyclooxygenases inhibitors), DAAO inhibitors(D-amino-acid oxidase inhibitors)

Therapeutic Areas

Infectious Diseases

Active Indication

Mycoses

Inactive Indication-

Originator Organization-

Active Organization-

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date-

Regulation-

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Structure/Sequence

Molecular FormulaC7H6O3

InChIKeyYGSDEFSMJLZEOE-UHFFFAOYSA-N

CAS Registry69-72-7

View All Structures (2)

Comprehensive investigation of multiple genomic data sets from targeted microbial taxa deposited in databases may provide substantial information to predict metabolic capabilities and ecological roles in different environments. This study is the first report that details the functional profiling of Thalassospira spp. that have repeatedly been found in polycyclic aromatic hydrocarbon (PAH)-exposed marine bacterial communities by using genomic data from a new isolate, Thalassospira strain GO-4, and other strains in databases.

29 Jun 2021·mBioQ1 · BIOLOGY

Production of Protocatechuic Acid from p -Hydroxyphenyl (H) Units and Related Aromatic Compounds Using an Aspergillus niger Cell Factory

Q1 · BIOLOGY

ArticleOA

Author: de Vries, Ronald P. ; Lubbers, Ronnie J. M.

Aromatic compounds have broad applications and are used in many industries, such as the cosmetic, food, fragrance, paint, plastic, pharmaceutical, and polymer industries. The majority of aromatic compounds are synthesized from fossil sources, which are becoming limited.

01 Jan 2018·Acta Crystallographica Section C Structural ChemistryQ4 · CHEMISTRY

The ephemeral dihydrate of sulfanilic acid

Q4 · CHEMISTRY

Article

Author: Langenstück, Stefanie ; Zhao, Chenchen ; Englert, Ulli

Evaporation of an aqueous solution of sulfanilic acid (systematic name: 4-aminobenzene-1-sulfonic acid) at 273 K affords a crystalline dihydrate, C6H7NO3S·2H2O. The organic molecule exists as a zwitterion; two zwitterions are aligned in an antiparallel fashion about a crystallographic centre of inversion. They interact directly via two N—H...O hydrogen bonds between the ammonium group of one zwitterion and the sulfonate group of its symmetry-related counterpart, and their aromatic rings are π-stacked, with an interplanar distance of 3.533 (3) Å. One of the cocrystallized water molecules connects the resulting pairs into layers and the second crosslinks the layers into a three-dimensional network. All H atoms connected to N or O atoms find acceptors in suitable geometries. In the resulting crystal, polar and hydrogen-bond-dominated slabs alternate with stacks of organic arene rings. Although the new dihydrate shows efficient space filling, with a packing coefficient of 75.7%, it is unstable and undergoes fast desolvation at room temperature. In this process, the orthorhombic ansolvate forms as a pure phase.

100 Deals associated with Salicylic acid/Benzoic Acid

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