Ranitidine Bismuth Citrate

In this study, a novel hybrid CoFe layered metal oxide (CoFeLMO) membrane was developed by integrating metal-organic framework (MOF) MIL(100)Fe and polyethylene glycol (PEG), designed specifically for peroxymonosulfate (PMS)-based advanced oxidation processes.The uniqueness of this research lies in the innovative incorporation of LMO, MOF, and PEG nanosheets onto a polyethersulfone (PES) substrate, creating a highly efficient catalytic membrane for the simultaneous removal of pharmaceutical micropollutants and nanoplastics (NPs).Among various configurations, the LMO-MOF-PEG membrane, with 20% MOF (0.025 M) and 0.5 g of PEG, demonstrated superior performance, achieving remarkable removal efficiencies of 99.5% for ranitidine and 98.5% for NPs.This membrane also exhibited outstanding operational efficiency, achieving a flux of 1600 L/m2/h/bar at a low PMS concentration of 0.2 mM.The degradation of ranitidine was driven by both reactive species (SO^•-₄, ^•OH and O^•-₂) and non-reactive species (singlet ¹O₂), with SO^•-₄ playing a dominant role.Post-activation anal. revealed the presence of Co²⁺ and Fe²⁺ in both + II and + III oxidation, indicating the active participation of metal plots in the degradation process and confirming the membrane's reusability.The membrane demonstrated exceptional durability, maintaining a flux recovery ratio of 97-99% across 10 filtration cycles, even under harsh chem. conditions and across a wide pH range (2-12).Furthermore, Co leaching was minimal (2-21μg/L) over a broad pH spectrum, even after 15 days of immersion in water.