[Translation] A randomized, double-blind, placebo-controlled, dose-escalating Phase I clinical trial to evaluate the safety/tolerability and pharmacokinetic characteristics of a single dose of HW211026 ointment in healthy volunteers
主要目的:评价 HW211026 软膏在健康受试者中单次给药的安全性、耐受性;次要目的:1.探索 HW211026 软膏在健康受试者中单次给药的药代动力学特征,2.比较HW211026 软膏在健康受试者中大腿屈侧和面部单次给药的药代动力学和安全性,3.单次给药代谢产物的鉴定。
[Translation] Main objective: To evaluate the safety and tolerability of a single dose of HW211026 ointment in healthy subjects; Secondary objectives: 1. To explore the pharmacokinetic characteristics of a single dose of HW211026 ointment in healthy subjects, 2. To compare the pharmacokinetics and safety of a single dose of HW211026 ointment to the thigh flexor and face in healthy subjects, 3. To identify the metabolites of a single dose.