Last update 21 Apr 2025

LBL-043

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
LBL 043, LBL043
Target
CD3 x LILRB4
Action
stimulants, inhibitors
Mechanism
CD3 stimulants(T cell surface glycoprotein CD3 stimulants), LILRB4 inhibitors(Leukocyte immunoglobulin-like receptor subfamily B member 4 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
Multiple MyelomaChronic Myelogenous LeukemiaTreatment related acute myeloid leukaemia
Inactive Indication-
Originator Organization
Nanjing Leads Biolabs Co., Ltd.Nanjing Leads Biolabs Co., Ltd.
Active Organization
Nanjing Leads Biolabs Co., Ltd.Nanjing Leads Biolabs Co., Ltd.
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with LBL-043
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100 Translational Medicine associated with LBL-043
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100 Patents (Medical) associated with LBL-043
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100 Deals associated with LBL-043
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple MyelomaPreclinical
China
Nanjing Leads Biolabs Co., Ltd.Nanjing Leads Biolabs Co., Ltd.
30 Apr 2025
Chronic Myelogenous LeukemiaPreclinical
China
Nanjing Leads Biolabs Co., Ltd.Nanjing Leads Biolabs Co., Ltd.
10 Apr 2024
Treatment related acute myeloid leukaemiaPreclinical
China
Nanjing Leads Biolabs Co., Ltd.Nanjing Leads Biolabs Co., Ltd.
14 Mar 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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