Last update 20 Mar 2025

Gossypol/Phenformin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Gossypol+Phenformin, Starvanip
+ [3]
Target
PRKAB1 x Reactive oxygen species
Action
activators, modulators, scavengers
Mechanism
PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), Reactive oxygen species modulators, Reactive oxygen species scavengers
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Advanced Malignant Solid Neoplasm
Originator Organization
National Cancer Center KoreaNational Cancer Center Korea
Active Organization-
Inactive Organization
Haim Bio Co., Ltd.Haim Bio Co., Ltd.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC10H15N5
InChIKeyICFJFFQQTFMIBG-UHFFFAOYSA-N
CAS Registry114-86-3
View All Structures (2)

Related

1
Clinical Trials associated with Gossypol/Phenformin
NCT04262739
/ Unknown statusPhase 1
Open-label, Phase I Clinical Trial to Assess the Maximum Tolerated Dose (MTD), Safety and Efficacy of NYH817G and NYH100P in Monotherapy and Combination in Patients With Advanced Solid Tumors Who Have Failed Approved Standard Therapies
100 Clinical Results associated with Gossypol/Phenformin
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100 Translational Medicine associated with Gossypol/Phenformin
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100 Patents (Medical) associated with Gossypol/Phenformin
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100 Deals associated with Gossypol/Phenformin
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
South Korea
Haim Bio Co., Ltd.Haim Bio Co., Ltd.
18 Dec 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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