Last update 12 Dec 2024

Gossypol/Phenformin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Gossypol+Phenformin, Starvanip, NYH-817100
+ [3]
Target
PRKAB1 x Reactive oxygen species
Mechanism
PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), Reactive oxygen species modulators, Reactive oxygen species scavengers
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication-
Originator Organization
National Cancer Center KoreaNational Cancer Center Korea
Active Organization
National Cancer Center KoreaNational Cancer Center KoreaHaim Bio Co., Ltd.Haim Bio Co., Ltd.Yonsei University Health SystemYonsei University Health System
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC10H15N5
InChIKeyICFJFFQQTFMIBG-UHFFFAOYSA-N
CAS Registry114-86-3
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Related

1
Clinical Trials associated with Gossypol/Phenformin
NCT04262739 / Unknown statusPhase 1
Open-label, Phase I Clinical Trial to Assess the Maximum Tolerated Dose (MTD), Safety and Efficacy of NYH817G and NYH100P in Monotherapy and Combination in Patients With Advanced Solid Tumors Who Have Failed Approved Standard Therapies
100 Clinical Results associated with Gossypol/Phenformin
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100 Translational Medicine associated with Gossypol/Phenformin
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100 Patents (Medical) associated with Gossypol/Phenformin
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100 Deals associated with Gossypol/Phenformin
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPhase 1-
National Cancer Center KoreaNational Cancer Center Korea
-
NeoplasmsPhase 1-
Yonsei University Health SystemYonsei University Health System
-
NeoplasmsPhase 1-
Haim Bio Co., Ltd.Haim Bio Co., Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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