Last update 21 Nov 2024

Oxymetazoline Hydrochloride/Chlorpheniramine Maleate/Glycyrrhizinate dipotassium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
盐酸羟甲唑啉/马来酸扑尔敏/甘草酸二钾, 코메키나플러스나잘스프레이
Target
11β-HSD1 x H1 receptor x α1A-AR
Mechanism
11β-HSD1 inhibitors(Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitors), H1 receptor antagonists(Histamine H1 receptor antagonists), α1A-AR agonists(Alpha-1a adrenergic receptor agonists)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesOtorhinolaryngologic Diseases+ [1]
Active Indication
Common ColdRhinitis, AllergicSinusitis
Inactive Indication-
Originator Organization
Daewoong Pharmaceutical Co., Ltd.Daewoong Pharmaceutical Co., Ltd.
Active Organization
Daewoong Pharmaceutical Co., Ltd.Daewoong Pharmaceutical Co., Ltd.
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
KR (07 Aug 2024),
Common ColdRhinitis, AllergicSinusitis
Regulation-
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Structure

Molecular FormulaC16H25ClN2O
InChIKeyBEEDODBODQVSIM-UHFFFAOYSA-N
CAS Registry2315-02-8
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Related

100 Clinical Results associated with Oxymetazoline Hydrochloride/Chlorpheniramine Maleate/Glycyrrhizinate dipotassium
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100 Translational Medicine associated with Oxymetazoline Hydrochloride/Chlorpheniramine Maleate/Glycyrrhizinate dipotassium
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100 Patents (Medical) associated with Oxymetazoline Hydrochloride/Chlorpheniramine Maleate/Glycyrrhizinate dipotassium
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100 Deals associated with Oxymetazoline Hydrochloride/Chlorpheniramine Maleate/Glycyrrhizinate dipotassium
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Common Cold
KR
Daewoong Pharmaceutical Co., Ltd.Daewoong Pharmaceutical Co., Ltd.
07 Aug 2024
Rhinitis, Allergic
KR
Daewoong Pharmaceutical Co., Ltd.Daewoong Pharmaceutical Co., Ltd.
07 Aug 2024
Sinusitis
KR
Daewoong Pharmaceutical Co., Ltd.Daewoong Pharmaceutical Co., Ltd.
07 Aug 2024
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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