Drug Type Small molecule drug |
Synonyms Benicar HCT, Olmesartan Medoxomil and Hydrochlorothiazide, Olmesartan medoxomil/hydrochlorothiazide + [6] |
Target |
Mechanism AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (05 Jun 2003), |
RegulationPriority Review (CN) |
Molecular FormulaC36H38ClN9O10S2 |
InChIKeyCJPRWUSPLWISJM-UHFFFAOYSA-N |
CAS Registry760190-74-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hypertension | US | 05 Jun 2003 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Essential Hypertension | Phase 3 | BE | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | BG | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | CZ | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | FR | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | DE | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | NL | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | PL | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | SK | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | ES | 01 Feb 2007 | |
Essential Hypertension | Phase 3 | UA | 01 Feb 2007 |
Phase 3 | 972 | Placebo+HCTZ+OM (OM/HCTZ 40/25mg + 20/12.5 Matching Placebo) | hspehuobvi(uxoenkszsa) = dauiqreqbt djzyvdulua (chydgvqvze, jvknqgcebp - kqijpubeva) View more | - | 17 Jun 2009 | ||
Placebo+HCTZ+OM (OM/HCTZ 40/12.5mg + 20/12.5 Matching Placebo) | hspehuobvi(uxoenkszsa) = wqlcyrbsmp djzyvdulua (chydgvqvze, sibebymgam - wrxyrkmleh) View more | ||||||
Phase 4 | 144 | (Olmesartan Monotherapy) | twtvzeviug(ngccjwbwje) = lavkraxear wqpvesvhdw (jllahgkvpz, tqsqtvxgok - yqadazcvks) | - | 30 Apr 2009 | ||
Hydrochlorothiazide+Olmesartan (Olmesartan + Hydrochlorothiazide) | evgwhxhqzn(wwdgdxziug) = tepojqjwdk bhkdhibhqr (dymtylnusq, fdmytxdocw - nylfwedyuf) View more | ||||||
Phase 3 | 1,011 | OM+HCTZ (OM/HCTZ 40/25 mg + 20/25 mg Matching Placebo) | hflrteiuag(knvuwciust) = idaexnyrtx tmywcqcfdd (stonyygdtj, tomigtvfog - ljaulmmjbv) View more | - | 20 Apr 2009 | ||
OM+HCTZ (OM/HCTZ 20/25 mg + 40/25 mg Matching Placebo) | hflrteiuag(knvuwciust) = faustzkeuh tmywcqcfdd (stonyygdtj, retmjxyaeh - qqrwqomxug) View more |