Last update 20 Mar 2025

GW3965-PEG4-VH032

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
Target
LXR
Action
degraders
Mechanism
LXR degraders(Liver X receptor degraders)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication
Diabetes MellitusHypercholesterolemia
Inactive Indication-
Originator Organization-
Active Organization
National Institute of Health SciencesNihon UniversityNihon University
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC65H78ClF3N6O10S
InChIKeyAVWXVADQEYZTET-ZXZGEIHWSA-N
CAS Registry-

Related

100 Clinical Results associated with GW3965-PEG4-VH032
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100 Translational Medicine associated with GW3965-PEG4-VH032
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100 Patents (Medical) associated with GW3965-PEG4-VH032
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1
Literatures (Medical) associated with GW3965-PEG4-VH032
Frontiers in ChemistryQ3 · CHEMISTRY
Development of Agonist-Based PROTACs Targeting Liver X Receptor
Q3 · CHEMISTRY
100 Deals associated with GW3965-PEG4-VH032
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes MellitusPreclinical
Japan
National Institute of Health Sciences
26 May 2021
Diabetes MellitusPreclinical
Japan
Nihon UniversityNihon University
26 May 2021
HypercholesterolemiaPreclinical
Japan
National Institute of Health Sciences
26 May 2021
HypercholesterolemiaPreclinical
Japan
Nihon UniversityNihon University
26 May 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
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Clinical Trial

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Approval

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Regulation

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