Last update 03 Sep 2026

INCB-177054

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
INCB-177054, INCB177054
Target
DGKA x DGKζ
Action
inhibitors
Mechanism
DGKA inhibitors(diacylglycerol kinase alpha inhibitors), DGKζ inhibitors(diacylglycerol kinase zeta inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Advanced Malignant Solid NeoplasmMetastatic Solid Tumor
Originator Organization
Incyte Corp.Incyte Corp.
Active Organization-
Inactive Organization
Incyte Corp.Incyte Corp.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with INCB-177054
NCT06873789
/ TerminatedPhase 1/2
A Phase 1/2, Open-Label, Multicenter Study of INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors
100 Clinical Results associated with INCB-177054
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100 Translational Medicine associated with INCB-177054
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100 Patents (Medical) associated with INCB-177054
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100 Deals associated with INCB-177054
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
United States
Incyte Corp.Incyte Corp.
30 Jun 2025
Metastatic Solid TumorPhase 2
United States
Incyte Corp.Incyte Corp.
30 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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