Last update 30 Aug 2025

CRIB (NT-4/5)(CytoTherapeutics/Genentech)

Overview

Basic Info

Drug Type
Cell therapy
Synonyms-
Target
NT-4
Action
modulators
Mechanism
NT-4 modulators(neurotrophin 4 modulators)
Therapeutic Areas
Nervous System DiseasesCardiovascular DiseasesCongenital Disorders+ [4]
Active Indication-
Inactive Indication
Diabetic RetinopathyGlaucomaHearing Disorders+ [4]
Originator Organization
Genentech, Inc.Genentech, Inc.
Active Organization-
Inactive Organization
Genentech, Inc.Genentech, Inc.Microbot Medical, Inc.Microbot Medical, Inc.
License Organization-
Drug Highest PhaseDiscontinuedDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CRIB (NT-4/5)(CytoTherapeutics/Genentech)
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100 Translational Medicine associated with CRIB (NT-4/5)(CytoTherapeutics/Genentech)
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100 Patents (Medical) associated with CRIB (NT-4/5)(CytoTherapeutics/Genentech)
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100 Deals associated with CRIB (NT-4/5)(CytoTherapeutics/Genentech)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic RetinopathyDiscovery
United States
Microbot Medical, Inc.Microbot Medical, Inc.
-
Diabetic RetinopathyDiscovery
United States
Genentech, Inc.Genentech, Inc.
-
GlaucomaDiscovery
United States
Genentech, Inc.Genentech, Inc.
-
GlaucomaDiscovery
United States
Microbot Medical, Inc.Microbot Medical, Inc.
-
Hearing DisordersDiscovery
United States
Genentech, Inc.Genentech, Inc.
-
Huntington DiseaseDiscovery
United States
Genentech, Inc.Genentech, Inc.
-
Motor Neuron DiseaseDiscovery
United States
Microbot Medical, Inc.Microbot Medical, Inc.
-
Motor Neuron DiseaseDiscovery
United States
Genentech, Inc.Genentech, Inc.
-
Parkinson DiseaseDiscovery
United States
Microbot Medical, Inc.Microbot Medical, Inc.
-
Parkinson DiseaseDiscovery
United States
Genentech, Inc.Genentech, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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