Last update 27 Jan 2026

FB-1003

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
4B03-04, FB 1003, FB-1003
Target
TrkA
Action
activators
Mechanism
TrkA activators(Nerve growth factor receptor Trk-A activators)
Therapeutic Areas
Immune System DiseasesNervous System DiseasesSkin and Musculoskeletal Diseases+ [1]
Active Indication
Osteoarthritis, KneeChronic PainArthritis Pain
Inactive Indication-
Originator Organization
4B Technologies (Beijing) Co., Limited4B Technologies (Beijing) Co., Limited
Active Organization
Fubei Biotechnology Suzhou Co. Ltd.Fubei Biotechnology Suzhou Co. Ltd.4B Technologies (Beijing) Co., Limited4B Technologies (Beijing) Co., Limited
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with FB-1003
NCT06343714
/ RecruitingPhase 1
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability and Pharmacokinetics of Escalating Single and Multiple Doses of FB1003 in the Healthy and Osteoarthritis Pain Subjects
100 Clinical Results associated with FB-1003
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100 Translational Medicine associated with FB-1003
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100 Patents (Medical) associated with FB-1003
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100 Deals associated with FB-1003
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, KneePhase 1
Australia
4B Technologies (Beijing) Co., Limited4B Technologies (Beijing) Co., Limited
07 Apr 2024
Chronic PainPhase 1
China
4B Technologies (Beijing) Co., Limited4B Technologies (Beijing) Co., Limited
09 Aug 2022
Arthritis PainPhase 1
Australia
4B Technologies (Beijing) Co., Limited4B Technologies (Beijing) Co., Limited
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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