Last update 16 May 2025

STI-8591

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AC 0939, AC-0939, AC0939
+ [3]
Target
FLT3
Action
inhibitors
Mechanism
FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersHemic and Lymphatic Diseases
Active Indication
Acute Myeloid LeukemiaHepatocellular Carcinoma
Inactive Indication-
Originator Organization
Hangzhou ACEA Pharmaceutical Research Co. Ltd.Hangzhou ACEA Pharmaceutical Research Co. Ltd.Zhejiang ACEA Pharmaceutical Co., Ltd.Zhejiang ACEA Pharmaceutical Co., Ltd.
Active Organization
Zhejiang ACEA Pharmaceutical Co., Ltd.Zhejiang ACEA Pharmaceutical Co., Ltd.Hangzhou ACEA Pharmaceutical Research Co. Ltd.Hangzhou ACEA Pharmaceutical Research Co. Ltd.ACEA Therapeutics, Inc.ACEA Therapeutics, Inc.
Inactive Organization-
License Organization
Sorrento Therapeutics, Inc.Sorrento Therapeutics, Inc.ACEA Therapeutics, Inc.ACEA Therapeutics, Inc.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with STI-8591
NCT05947344
/ RecruitingPhase 1
A Multicenter, Open, Dose Escalation and Dose Expansion Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of STI-8591 in Subjects With Advanced Acute Myeloid Leukemia (AML)
100 Clinical Results associated with STI-8591
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100 Translational Medicine associated with STI-8591
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100 Patents (Medical) associated with STI-8591
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100 Deals associated with STI-8591
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 1
China
Zhejiang ACEA Pharmaceutical Co., Ltd.Zhejiang ACEA Pharmaceutical Co., Ltd.
04 Dec 2023
Acute Myeloid LeukemiaPhase 1
China
Hangzhou ACEA Pharmaceutical Research Co. Ltd.Hangzhou ACEA Pharmaceutical Research Co. Ltd.
04 Dec 2023
Hepatocellular CarcinomaPhase 1
China
ACEA Therapeutics, Inc.ACEA Therapeutics, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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