Last update 12 Dec 2024

NRC-2694

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
NRC 2694-A, NRC 2694A, NRC-2694-A
+ [2]
Target
EGFR
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists)
Therapeutic Areas
Neoplasms
Active Indication
Squamous cell carcinoma of head and neck metastaticSquamous Cell Carcinoma
Inactive Indication
Breast Cancer
Originator Organization
Natco SA
Active Organization
Natco SANATCO Pharma Ltd.NATCO Pharma Ltd.
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC24H26N4O3
InChIKeyWBKHQQZRHCECKK-UHFFFAOYSA-N
CAS Registry936446-61-6

Related

3
Clinical Trials associated with NRC-2694
NCT05283226 / RecruitingPhase 2
A Phase 2 Multicenter, Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination with Paclitaxel in Patients with Recurrent And/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy
CTRI/2019/06/019649 / RecruitingPhase 2
A Phase II Clinical Study to evaluate the efficacy and safety of NRC-2694-A in patients with recurrent Head and Neck Squamous Cell Carcinoma
CTRI/2014/01/004293 / CompletedPhase 1
A Phase I Clinical Study to evaluate the safety, pharmacokinetics and anti-tumor activity of NRC-2694-A in patients with advanced Solid Malignancies
100 Clinical Results associated with NRC-2694
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100 Translational Medicine associated with NRC-2694
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100 Patents (Medical) associated with NRC-2694
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100 Deals associated with NRC-2694
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Squamous cell carcinoma of head and neck metastaticPhase 2
US
NATCO Pharma Ltd.NATCO Pharma Ltd.
30 Sep 2022
Squamous cell carcinoma of head and neck metastaticPhase 2
IN
NATCO Pharma Ltd.NATCO Pharma Ltd.
30 Sep 2022
Squamous Cell CarcinomaPhase 2-
Natco SA
-
Breast CancerPhase 1
IN
NATCO Pharma Ltd.NATCO Pharma Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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