Last update 23 Jan 2025

PIP-199

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
FANCM x RMI1 x RMI2
Mechanism
FANCM inhibitors(FA complementation group M inhibitors), RMI1 inhibitors(RecQ mediated genome instability 1 inhibitors), RMI2 inhibitors(RecQ mediated genome instability 2 inhibitors)
Therapeutic Areas
Immune System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication
Bloom SyndromeFanconi Anemia
Inactive Indication-
Originator Organization
The University of Sydney
Active Organization
The University of Sydney
Inactive Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC27H28N4O3
InChIKeyROTCTSYSZSYNHB-UHFFFAOYSA-N
CAS Registry622795-76-0

Related

100 Clinical Results associated with PIP-199
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100 Translational Medicine associated with PIP-199
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100 Patents (Medical) associated with PIP-199
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1
Literatures (Medical) associated with PIP-199
24 Aug 2023Journal of medicinal chemistryQ1 · MEDICINE
Mannich Base PIP-199 Is a Chemically Unstable Pan-Assay Interference Compound.
Q1 · MEDICINE
100 Deals associated with PIP-199
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Bloom SyndromeDiscovery
AU
The University of Sydney
09 Aug 2023
Fanconi AnemiaDiscovery
AU
The University of Sydney
09 Aug 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Approval

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Regulation

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