Last update 07 Nov 2024
ONO-4685
Last update 07 Nov 2024
Overview
Basic Info
Drug Type Bispecific T-cell Engager (BiTE) |
Synonyms ONO 4685, ONO4685 |
Target |
Mechanism CD3 modulators(T cell surface glycoprotein CD3 modulators), PD-1 modulators(Programmed cell death protein 1 modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
6
Clinical Trials associated with ONO-4685ONO-4685-05 : An Open-label, Non-randomized, Phase I Dose Escalation Study to Investigate the Tolerability and Safety of ONO-4685 Given as Monotherapy in Patients With Relapsed or Refractory T Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma(CLL/SLL)
An Open-label, Uncontrolled, Phase I Dose Escalation Study to Investigate the Tolerability and Safety of ONO-4685 Given as Monotherapy in Patients With Relapsed or Refractory T Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
ONO-4685-04:ONO-4685 Phase 1 study Single intravenous continuous infusion and subcutaneous administration study in Japanese healthy adult male subjects
100 Clinical Results associated with ONO-4685
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100 Translational Medicine associated with ONO-4685
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100 Patents (Medical) associated with ONO-4685
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100 Deals associated with ONO-4685
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Chronic Lymphocytic Leukemia | Phase 1 | JP | 01 Oct 2023 | |
| Small Lymphocytic Lymphoma | Phase 1 | JP | 01 Oct 2023 | |
| Plaque psoriasis | Phase 1 | MD | 25 Mar 2022 | |
| Plaque psoriasis | Phase 1 | RO | 25 Mar 2022 | |
| Plaque psoriasis | Phase 1 | GB | 25 Mar 2022 | |
| T-cell lymphoma recurrent | Phase 1 | US | 10 Dec 2021 | |
| T-cell lymphoma refractory | Phase 1 | US | 10 Dec 2021 | |
| Autoimmune Diseases | Phase 1 | EU | - | |
| Autoimmune Diseases | Phase 1 | JP | - | |
| Psoriasis | Phase 1 | - | - |
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