[Translation] Phase I clinical study on the safety, tolerability, pharmacokinetic characteristics and food effects of single/continuous administration of WXSH0408 capsules in healthy adult subjects
主要目的: 1)评估健康成人空腹条件下单次服用WXSH0408胶囊后的安全性和耐受性; 2)评估健康成人空腹条件下连续服用WXSH0408胶囊后的安全性和耐受性; 3)评估食物对健康成人服用WXSH0408胶囊后药代动力学特征的影响。 次要目的: 1)评估健康成人空腹条件下单次服用WXSH0408胶囊后的药代动力学特征; 2)评估健康成人连续服用WXSH0408胶囊后的药代动力学特征。
[Translation] Primary objectives: 1) To evaluate the safety and tolerability of WXSH0408 capsules after a single dose in healthy adults on an empty stomach; 2) To evaluate the safety and tolerability of WXSH0408 capsules after continuous administration in healthy adults on an empty stomach; 3) To evaluate the effect of food on the pharmacokinetic characteristics of WXSH0408 capsules after administration in healthy adults. Secondary objectives: 1) To evaluate the pharmacokinetic characteristics of WXSH0408 capsules after a single dose in healthy adults on an empty stomach; 2) To evaluate the pharmacokinetic characteristics of WXSH0408 capsules after continuous administration in healthy adults.