Last update 19 Apr 2025

CHT-102

Overview

Basic Info

Drug Type
CAR-T
Synonyms
CHT102 allogeneic CAR T cells(Tianjin Medical University Cancer Institute and Hospital), CHT-102
Target
MSLN
Action
inhibitors
Mechanism
MSLN inhibitors(Mesothelin inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Pancreatic CancerMesothelin positive Solid Tumors
Inactive Indication-
Originator Organization
Tianjin Medical University Cancer Institute and HospitalTianjin Medical University Cancer Institute and Hospital
Active Organization
Tianjin Medical University Cancer Institute and HospitalTianjin Medical University Cancer Institute and HospitalNanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with CHT-102
NCT06760364
/ RecruitingPhase 1IIT
A Single-Arm, Open-Label, Phase I Study of CHT102 for MSLN-Positive Advanced Pancreatic Cancer
NCT06717022
/ RecruitingNot ApplicableIIT
A Clinical Study of CHT102, a Universal Chimeric Antigen Receptor T-Cell Immunotherapy(U CAR-T) for Mesothelin(MSLN) Positive Advanced Solid Tumors: a Single-arm, Open-label, Dose Escalation and Expansion Clinical Study
100 Clinical Results associated with CHT-102
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100 Translational Medicine associated with CHT-102
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100 Patents (Medical) associated with CHT-102
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100 Deals associated with CHT-102
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 1
China
Nanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
25 Dec 2024
Mesothelin positive Solid TumorsClinical
China
Tianjin Medical University Cancer Institute and HospitalTianjin Medical University Cancer Institute and Hospital
06 May 2024
Mesothelin positive Solid TumorsClinical
China
Nanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
06 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Approval

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Regulation

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