Last update 26 Jul 2025

PBI-4425

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PBI 4425, PBI4425
Target
GPR40 x GPR84
Action
antagonists, agonists
Mechanism
G-protein coupled receptor 84 antagonists, GPR40 agonists(Free fatty acid receptor 1 agonists)
Therapeutic Areas
Immune System DiseasesEndocrinology and Metabolic DiseaseRespiratory Diseases+ [3]
Active Indication-
Inactive Indication
Acute Lung InjuryDiabetic NephropathiesPulmonary Fibrosis+ [1]
Originator Organization
Liminal BioSciences, Inc.Liminal BioSciences, Inc.
Active Organization-
Inactive Organization
Liminal BioSciences, Inc.Liminal BioSciences, Inc.
License Organization
Liminal BioSciences, Inc.Liminal BioSciences, Inc.Jiangsu Rongyu Pharmaceutical Co. Ltd.Jiangsu Rongyu Pharmaceutical Co. Ltd.
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with PBI-4425
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100 Translational Medicine associated with PBI-4425
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100 Patents (Medical) associated with PBI-4425
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100 Deals associated with PBI-4425
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pulmonary FibrosisPreclinical
Canada
Liminal BioSciences, Inc.Liminal BioSciences, Inc.
12 May 2020
Acute Lung InjuryPreclinical
Canada
Liminal BioSciences, Inc.Liminal BioSciences, Inc.
02 May 2020
SclerodermaPreclinical
Canada
Liminal BioSciences, Inc.Liminal BioSciences, Inc.
31 Dec 2017
Diabetic NephropathiesPreclinical
Canada
Liminal BioSciences, Inc.Liminal BioSciences, Inc.
14 May 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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