Last update 04 Nov 2024

5(R)-Hydroxytriptolide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
5(R)-5-hydroxytriptolide, 5-Hydroxytriptolide, Hydroxytriptolide
+ [7]
Target
Mechanism
NOS2 inhibitors(Nitric oxide synthase, inducible inhibitors), Immunostimulants
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC20H24O7
InChIKeyOKRSVUYYCJPECG-LFGMFVMYSA-N
CAS Registry583028-68-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Rheumatoid ArthritisPhase 2
CN
22 Jun 2020
Rheumatoid ArthritisPhase 2
CN
22 Jun 2020
Acquired Immunodeficiency SyndromePhase 2
CN
25 Dec 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
149
cwekxqbupl(blmmoyfijx) = TEAEs were reported in 41 of 46 (89.1%) participants in HT8 group, 43 of 51 (84.3%) in LT8, and 42 of 52 (80.7%) in PL group eotbqnvnzf (utvszefdhd )
Positive
01 May 2023
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Approval

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Regulation

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