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Clinical Trials associated with Novel Oral Polio Vaccine Type 3 (nOPV3)(Viroclinics Biosciences)A Phase 2, Randomized, Observer-Blind, Controlled, Age De-escalation, Dosage Escalation Study to Assess the Safety and Immunogenicity of a Novel Live Attenuated Type 3 Oral Poliomyelitis Vaccine in Healthy Young Children, Infants, and Neonates in Panama
The purpose of this clinical trial is to assess the safety and tolerability (primary objective), immunogenicity (primary and secondary objectives), fecal shedding of vaccine viruses (secondary objective) and the potential for neurovirulence of shed virus (secondary objective) of a novel oral polio type 3 vaccine, nOPV3, as compared to Sabin monovalent type 3 vaccine controls (mOPV3), in healthy young children (192 subjects), infants (860 subjects), and neonates (480 subjects).
A First-in-human, Phase 1, Randomized, Observer-blind, Controlled Study to Assess the Safety and Immunogenicity of Novel Live Attenuated Type 1 and Type 3 Oral Poliomyelitis Vaccines in Healthy Adults
The purpose of this study is to assess the safety (primary objective), the ability to trigger the production of antibodies (immunogenicity; a secondary objective) and presence of vaccine virus in the stool (fecal shedding; a secondary objective) of two novel oral polio vaccines (nOPV), novel oral poliomyelitis vaccine type 1 (nOPV1) and novel oral poliomyelitis vaccine type 3 (nOPV3), as compared to Sabin strain monovalent oral poliomyelitis vaccine (mOPV) controls, in healthy adults.
100 Clinical Results associated with Novel Oral Polio Vaccine Type 3 (nOPV3)(Viroclinics Biosciences)
100 Translational Medicine associated with Novel Oral Polio Vaccine Type 3 (nOPV3)(Viroclinics Biosciences)
100 Patents (Medical) associated with Novel Oral Polio Vaccine Type 3 (nOPV3)(Viroclinics Biosciences)
100 Deals associated with Novel Oral Polio Vaccine Type 3 (nOPV3)(Viroclinics Biosciences)