Delving into the Latest Updates on Botulinum toxin type A(Mentor Corp) with Synapse

Overview

Basic Info

Drug Type

Toxin

Synonyms

Botulinum toxin A, PurTox

Target

SNAP25

Mechanism

SNAP25 inhibitors(Synaptosomal-associated protein 25 inhibitors)

Therapeutic Areas

Skin and Musculoskeletal DiseasesNervous System DiseasesOther Diseases

Active Indication-

Inactive Indication

cervical dystoniaCongenital TorticollisSkin Diseases+ [1]

Originator Organization

Mentor Worldwide LLC

Active Organization-

Inactive Organization

Mentor Worldwide LLC

Johnson & Johnson

Drug Highest PhaseDiscontinuedPhase 3

First Approval Date-

Regulation-

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The safety and efficacy of Mentor Purified Toxin, Botulinum Toxin Type A, Purified Neurotoxin, injected intramuscularly into the neck, is being evaluated as a treatment for painful and non-painful spasmodic torticollis/cervical dystonia. It is hypothesized that treatment will decrease symptom severity and will not have any significant side effects.

Start Date01 May 2006

Sponsor / Collaborator

Mentor Worldwide LLC

100 Clinical Results associated with Botulinum toxin type A(Mentor Corp)

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100 Translational Medicine associated with Botulinum toxin type A(Mentor Corp)

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100 Patents (Medical) associated with Botulinum toxin type A(Mentor Corp)

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19

Literatures (Medical) associated with Botulinum toxin type A(Mentor Corp)

01 Sep 2024·DERMATOLOGIC SURGERY

Using Neuromodulators to Improve Scar Formation, Keloids, Rosacea, and Antiaging

Review

Author: Ozog, David ; Wu, Woffles ; Rosales Santillan, Monica

BACKGROUND:

Botulinum toxin A (BoNT-A) treatment has many uses in dermatology. Its mechanism of action and long-term effects for scar formation, rosacea, and antiaging are still being investigated.

OBJECTIVE:

To conduct a literature review on BoNT-A to further investigate its use in scar formation, rosacea, and antiaging.

METHODS:

A literature review was conducted using PubMed on botulinum toxin treatment for scar formation, rosacea, and antiaging. Studies discussing the toxin mechanism of action and treatment algorithm were included. The authors also provided their personal experience in BoNT-A use for these 3 conditions.

RESULTS:

The mechanism of action of Botulinum toxin A in improving scar formation, rosacea, and antiaging is now better understood. While it is effective in the short term, little is still known about how frequently treatment needs to be repeated and if there are any long-term effects.

CONCLUSION:

While in vitro studies have supporting evidence on the mechanism of action of BoNT-A on scar formation, rosacea, and antiaging, further studies are needed to identify long-term treatment effects.

01 Nov 2022·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...

Article

Author: Lohmeyer, Jörn Andreas ; Keck, Maike Katharina ; Shahmiri-Zimmermann, Shanly

01 Mar 2014·Plastic and reconstructive surgeryQ2 · MEDICINE

Abstract 5

Q2 · MEDICINE

Article

Author: Neumeister, Michael W ; Webb, Kelli N ; Berry, Nada N ; Bueno, Reuben A

100 Deals associated with Botulinum toxin type A(Mentor Corp)

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External Link

KEGG	Wiki	ATC	Drug Bank
D00783	Botulinum toxin type A(Mentor Corp)	-	DB00083

R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Skin Diseases	Phase 3	-	Johnson & Johnson	-
Torticollis	Phase 2	-	Johnson & Johnson	-
cervical dystonia	Phase 1	US	Mentor Worldwide LLC	01 May 2006
Congenital Torticollis	Phase 1	US	Mentor Worldwide LLC	01 May 2006